Buffalo traffic isn't notoriously AWFUL, but it's not real great all the time, either.
There might be an area or two that gives you anxiety, miles before you hit it each morning/afternoon.
For me, there's one particular area if I'm travelling from Buffalo to Main Street in Williamsville that I start sweating about, as soon as I get on the 33...
Think of all the times you've headed down Broadway through Lancaster and Alden to Darien Lake for a concert. Or when you've used Southwestern Boulevard to get to the Ralph Wilson Stadium for a Buffalo Bills game. What do those two roads have in common?
They're both designated U-S Route 20.